Acharya, s r acharya, n s bhangale, j o shah, s k pandya, s s. Mar 15, 20 the hepatoprotective activity can be most easily evaluated screened with the aid of several model systems of liver damage in experimental animals. Evaluation of the antioxidant activity of sida cordifolia. Effect of some indian herbs on macrophage functions in. Pdf molecular diversity analysis of asparagus racemosus and. Phytochemical test and cytotoxic activity of macroalgae eucheuma cotton. Preclinical studies have shown that amalkadi ghrita 100 and 300 mgkg, p. Some hepatoprotective activity of boerhaavia diffusa l. In recent years, the popularity of medicinal plants as a remedy has been increased manifold due to having minimal adverse effects. Protective effects of asparagusracemosus on oxidative damage.
Asparagus racemosus roots is partly mediated by inhibition of carbohydrate digestion and absorp. Asparagaceae commonly known as shatavari in india, is a wellknown traditional rasayana drug used for variety of ailments. In evaluation of hepatoprotective activity of asparagus racemosus root vitro antioxidant activity of asparagus racemosus root. Diabetes was induced in male wister albino rats by the administration of single intraperitoneal injection of alloxan monohydrate 120 mgkg b. The extract having tremendous activities in all antioxidant assays by reducing lipid peroxidation and catalase activity. Preliminary evaluation of the hepatic protection by. Keeping this perspective, the present study was undertaken to investigate hepatoprotective activity and antioxidant role of the aqueous extract of. Antihyperglycaemic activity of asparagus racemosus roots is partly mediated by inhibition of carbohydrate digestion and absorption, and enhancement of. By s r acharya, n s acharya, j o bhangale, s k shah and s s pandya. Mar 18, 2010 hypolipidaemic and hepatoprotective effects of ethanolic and aqueous extracts from asparagus officinalis l. Administration of antioxidant could reduce the hepatic injury.
The current study aimed to compare the hypoglycemic, hypolipidemic and hepatoprotective effects of the ethanolic extract of asparagus racemosus eear linn. Hepatoprotective activity of achyrocline satureioideslam. Gastroduodenal ulcer protective activity of asparagus racemosus. Sitha institute of pharmaceutical sciences 2, hyderabad, andhra pradesh, india. The present study was designed to investigate the synergistic hepatoprotective effect of silymarin in combination with standardised extracts of picrorrhiza kurroa, phyllanthus amarus, tephrosia purpurea, asparagus racemosus plants against experimental hepatotoxicity induced by administration of paracetamol 3gkg. Liver has a pivotal role in regulation of physiological processes. Aqueous extract of asparagus racemosus root aear was evaluated for its hepatoprotective activities in rats. B, hepatoprotective activity of asparagus racemosus root on liver damage caused by paracetamol in rats, indian journal of novel drug delivery 2011, 32, 112117. Plant extracts with putative hepatoprotective activity. Asparagus racemosus is an ayurvedic rasayana, which finds mention in.
Shatavari is the main ayurvedic rejuvenative tonic for the female, as is. Sitha institute of pharmaceutical sciences 2, hyderabad, andhra pradesh. Hepatoprotective activities of plants are associated with phytochemicals such as alkaloids. Hepatoprotective effect of solanum xanthocarpum fruit. Anti arthritic activity of asparagus racemosus on adjuvant induced arthritis in rat. When compared to the controls, administering amalkadi ghrita reduced the levels of. Academics in hepatoprotective activity of asparagus racemosus. Invitro antioxidant, anticancer, and antiinflammatory. Identification of six phytochemical compounds from asparagus.
Investigation of polyphenol profile, antioxidant activity and. To investigate the hepatoprotective activity of asparagus racemosus against isoniazidinduced hepatotoxicity in male albino rats. Protective effects of asparagus the authors 2011 racemosus. Pdf hepatoprotective activity of asparagus racemosus. After five weeks of treatment, doses of 250 and 500 mgkg of asparagus were able. The investigation on antioxidant activity with the help of measuring the level of lipid per oxidation,glutathione,catalase and protein content. Apoptosis inducing activity of steroidal constituents from solanum xanthocarpum and asparagus racemosus. Hepatoprotective activity of the extracts was also demonstrable in vivo by the inhibition ofccl 4 induced formation of lipid peroxides in the liver of rats by pretreatment with the. You will be redirected to the full text document in the repository in a few seconds, if not click here. Protective effects of asparagusracemosus on oxidative damage in.
Velavan s, nagulendran k, mahesh r, hazeena begum v 2007. Terminalia bellerica, phytoconstituents, traditional use. However, till date no work has been reported on the hepatoprotective properties of this plant. Liposomal delivery systems for herbal extracts sciencedirect. The extract of asparagus racemosus functions as a hepatoprotective agent and this hepatoprotective activity of asparagus racemosus may be due normalization of impaired membrane function activity. Hypolipidaemic and hepatoprotective effects of ethanolic and. Protective effects of asparagusracemosus on oxidative. Antioxidant and hepatoprotective action of asparagus racemosus willd. View academics in hepatoprotective activity of asparagus racemosus on academia. Ochratoxin a ota is a mycotoxin consisting of a dihydroisocoumarin moiety linked through its carboxyl group to l. Hepatoprotective activity of six polyherbal formulations in paracetamol induced liver toxicity in mice. The hepatoprotective action of asparagus racemosus root extracts has been reported 23. Hypocholesterolemic and hepatoprotective effects of triguero.
Hypolipidaemic and hepatoprotective effects of ethanolic. Liver damage was induced by oral administration of. Hepatoprotective effect of solanum xanthocarpum fruit extract. Asparagus racemosus, glutathione, hepatoprotection, lipid peroxidation, paracetamol, serum marker enzymes. Additionally, it shows hepatoprotective, antioxidant. Gastroprotective effects of herbal medicines roots taylor. An animal study found shatavari to have antilithiatic effects, lending support to traditional uses. Pdf research article hepatoprotective activity of asparagus. O m fasalurahiman, m rupesh kumar, t tamizhmani, k mohamed niyas, pasumarthiphaneendra, b surendra. Pharmacognostical and phytochemical evaluation of root of. An evaluation of the antidiabetic properties asparagus africanus.
Pdf molecular diversity analysis of asparagus racemosus. Pdf hepatoprotective activity of asparagus racemosus root on. Mohammed ishaq 3 deccan school of pharmacy 1, hyderabad, andhra pradesh, india. In vitro antioxidant activities of root extract of asparagus racemosus. Introduction abnormal heightened levels of any or all lipids and or lipoproteins in the blood is defined as hyperlipidemia which is. In this study we made an attempt to evaluate the hepatoprotective activity of aqueous extracts of asparagus racemosus root aear on wistar rats. Studies across the globe clearly suggest the increase in microbial activity and galactogenic activity. Antioxidant and hepatoprotective action of asparagus. Recent studies on shatavari shatavari,asparagus racemosa. Hepatoprotective activity of asparagus racemosus root. Deccan school of pharmacy 1, hyderabad, andhra pradesh, india. Pdf aqueous extract of asparagus racemosus root aear was evaluated for its hepatoprotective activities in rats.
Animals exposed to isoniazide showed necrotic changes resulting in the release of hepatic enzymes aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase and. Effects of asparagus racemosus root extracts on serum lipid. Studies on hypoglycaemic activity of solanum xanthocarpum schrad. Hepatoprotective activity of asparagus racemosus root against carbon tetrachloride induced hepatotoxicity in albino rats december 2014 international journal of. To investigate the effects of asparagus racemosus ar root extract on.
Pdf antioxidant and hepatoprotective action of asparagus. Hepatotoxicity and the present herbal hepatoprotective scenario. Materials and methods media preparation for the propagation of asparagus racemosus murashige and skoogs ms media was used. Antihyperglycaemic activity of asparagus racemosus roots is partly. Pandya, journalindian journal of experimental biology, year2012, volume50 11.
Significant hepatoprotective activity of aqueous and ethanol extracts of v. Antioxidant and hepatoprotective action of asparagus racemosus. Academic sciences asian journal of pharmaceutical and. Asparagus racemosus functions as a hepatoprotective agent and this hepatoprotective activity of asparagus racemosus may be due normalization of impaired membrane function activity. Hepatoprotective activity of asparagus racemosus root on liver damage. The plant is a spinous undershrub, with tuberous, short rootstock bearing numerous succulent tuberous roots 30100 cm long and 12 cm thick that are silvery white or ash coloured externally and white internally. Hepatoprotective activity of asparagus racemosus root on liver damage caused by paracetamol in rats. The purpose of this study was designed to evaluate the hypolipidemic and hepatoprotective effects of ethanolic root extracts of asparagus racemosus eear linn. The present investigation has been designed to study the possible mechanism of aqueous extract of asparagus racemosus root on the different parameter against ccl 4 induced. Roots of asparagus racemosus and the leaves of aristolochia indica were used by the kaviraj to treat jaundice. Mohamed k, kumar satya b, phaneendra p, surendra b 2011. The ms powder was dissolved in double distilled water and ph of the prepared media was maintained at 5. Feb 01, 2021 asparagus racemosus root extract has been known as its antiinflammatory activity. Arthika s, shanthammal y, sheryl igal1 n, elankini p, pramod reddy g, gaidhani sn, ganesan r, hepatoprotective activity.
Fasalu rahiman om, rupesh kumar m, tamizh mani t, mohamed niyas k, satya kumar b, phaneendra p and surendra b. Comparative evaluation of antioxidant potential of. The present hepatic dysfunction in most of the cases reported due to investigation has been designed to study the possible inhalation of hepatotoxin. Hepatoprotective activity was resultant of inhibited production of free radicals, acting as a scavenger and reducing the free radical generation via inhibition of hepatic cyp2e1 activity. Department of pharmacology, institute of medical sciences, banaras hindu university, varanasi 221005, india. Potentiates the hypolipidemic and hepatoprotective activity of fenofibrate in alloxaninduced diabetic rats 1. Sangeetha shukla et al, 2006 were evaluated the protective effect of tb fruit extract and its active principle, gallic acid against ccl4 intoxication.
Shatavari asparagus racemosus shatavari is an herb used commonly in ayurvedic medicine for a variety of conditions, including adaptogenic, antibacterial, antiinflammatory, nephroprotective, immune modulation and antioxidant. Arthika s, shanthammal y, sheryl igal1 n, elankini p, pramod reddy g, gaidhani sn, ganesan r, hepatoprotective activity of the ethanolic extract of azima. The antioxidant activities of the crude hydroalcoholic extract ce and its four fractions viz. Diabetes mellitus is strongly connected with changes in lipid profile and also can cause damage of several organs like liver over a long period of time. Asparagus racemosus, glutathione, hepatoprotection, lipid. Asparagus racemosus, antioxidant activity, ccl4, hepatoprotection reactive oxygen species ros are mainly associated in the development of degenerative. Chemical constituents and medicinal properties of solanum. Phyllanthus emblica an overview sciencedirect topics.
Dec 01, 2011 kar dm, maharana l, pattnaik s, dash gk. In all test model systems, conditions for liver damage are implemented and an attempt is made to counteract this toxicosis with the substancepreparation under test. Use of herbal remedies as hepatoprotective therapy has been practised in. An update on ayurvedic herb convolvulus pluricaulis choisy.
Plant profile, phytochemistry and pharmacology of asparagus. Hepatoprotective activity o f aspargus racemosus roo t extract on lipopolysaccharide induced oxidative stress in rats. Mar 15, 2019 hepatoprotective activity o f aspargus racemosus roo t extract on lipopolysaccharide induced oxidative stress in rats. Pdf hepatoprotective activity of the alcohol extract of.
Sep 01, 1997 asparagus racemosus ar, withania somnifera ws, tinospora cordifolia tc and picrorhiza kurrooa pk have been found to enhance host resistance and reduce the side effects of other toxic agents. Sitoindoside x, an acylsterylglycoside, from the roots of sida cordifolia has been proved as an adaptogenic and immunostimulant ghosal et. Universal journal of pharmaceutical research 201 9. Immunomodulatory activity of asparagus racemosus on systemic th1th2 immunity. Pdf hepatoprotective activity of asparagus racemosus root. Antibacterial activity is the efficacy of the plant extract to inhibit the growth of.
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